Single Fluid Heating Cooling System

Single Fluid Heating Cooling System

Traditional Heating & Cooling Systems

Active Pharmaceutical Ingredient (API) manufacturing involves batch reaction, work-up, distillation, crystallization, hydrogenation, layer separation, filtration and drying as unit processes. Again, batch reaction involves heating and cooling stages ranging from -50°C to +250°C.
Traditionally, this was being done with multiple utilities such as chilled brine, chilled water, cooling water, hot water, low pressure steam, high pressure steam, thermic fluid etc.

Solution

Single fluid heating cooling systems (SFHC) / Temperature Control Unit (TCU) are coming-up as an ideal solution to overcome most of the limitations with traditional multiutility based heat transfer and control system. where high accuracy and wide temperature ranges are critical for the development of new compounds and API’s.

How it Works?

Single fluid heating cooling system is normally connected to a single reactor, where the Temperature of the system is varied as per the process requirement, Thus maintaining the constant temperature difference between the process and fluid temperature.
This gives precise control over heating and cooling cycle. Thus, not only the temperature is controlled as a critical process parameter but also the heating-and-cooling time is controlled as a critical parameter. This results in batch-to-batch consistency and higher yield.

Related Images

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